Quick answer
MuleSoft and Informatica are both owned by Salesforce, which completed its acquisition of Informatica on 18 November 2025. MuleSoft is an API-led application integration platform. Informatica is a data management platform covering ETL, data quality, governance and master data management. ONEiO is managed iPaaS: integration outcomes delivered as a service.
Integrations connect today's enterprise networked IT ecosystems. As you integrate even more apps, systems and cloud services, you need a solution that scales up with your growing needs.
In this article, we compare MuleSoft and Informatica, two of the largest integration platform as a service (iPaaS) vendors found in the market today.
Key takeaways
- Salesforce owns both. MuleSoft since 2018, Informatica since 18 November 2025, in a deal valued around $8bn. This is the single most important fact for anyone comparing them today.
- They solve different problems. MuleSoft is API-led application integration. Informatica is data management: ETL, data quality, governance and master data management.
- Comparing them is now partly a portfolio question. Ask Salesforce directly how the two roadmaps relate, where they overlap, and what the long-term plan is for each product line.
- Informatica is still operating multi-cloud. It expanded its Microsoft Fabric and Azure integration in March 2026, after the acquisition closed.
- Managed iPaaS is a different category. ONEiO operates the integration layer between business systems. It does not compete with Informatica on data pipelines or master data management.
What is MuleSoft
MuleSoft is a major player in the integration platform as a service (iPaaS) market focused on an API-led integrations. Acquired by Salesforce in 2018, MuleSoft is best known for its Anypoint Platform, which offers broad capabilities for API management and integration.
For ITSM professionals, MuleSoft's value lies in its ability to create a cohesive yet flexible integration network via its Anypoint Platform. Working like an enterprise service bus (ESB), Anypoint allows you to design, deploy, and manage APIs and integrations in a unified manner, supporting both SOA (Service-Oriented Architecture) and microservices environments.
In recent years, MuleSoft has expanded its focus into process automation, offering robotic process automation (RPA) and intelligent document processing (IDP) functionality. These areas bring MuleSoft's service offering closer to broad, intelligent automation platforms like Workato and UiPath.
What is Informatica
Informatica is a leader in enterprise cloud data management, providing comprehensive data integration solutions. With a focus on data-driven digital transformation, Informatica offers tools for data integration, data quality, and data governance.
Founded in 1993, Informatica has a long history in handling complex data environments. Its Intelligent Data Management Cloud (IDMC) platform provides a scalable and secure environment for managing data across multi-cloud and hybrid landscapes. Informatica’s services extend to data cataloging, data privacy, and AI-driven data processing.
MuleSoft vs. Informatica integration platform comparison
Let’s go through how MuleSoft and Informatica compare in five common integration scenarios: API management, data integration, B2B/EDI integration, application integration, and system integration.
API Management
MuleSoft's Anypoint Platform is built for API management. It provides an API Designer for creating RAML or OAS specifications, allowing you to define your API contract before implementation. An API Manager lets you set policies and monitor usage, giving you control over your API's behavior and performance. An API Portal offers documentation and interactive testing capabilities. Overall, MuleSoft gives you one of the most comprehensive solutions for managing API integrations.
Informatica Intelligent Cloud Services (IICS) allows you to create, manage, and monitor APIs for smooth communication between disparate software systems. Supporting REST and SOAP APIs, IICS provides tools for API design, deployment, and security, along with pre-built connectors and templates to expedite integration processes.
Data Integration
MuleSoft approaches data integration through its own DataWeave data language, which allows for complex data manipulations. The AnyPoint platform supports batch processing for handling large volumes of data, and works with various data formats including XML, JSON, and CSV. The platform also has a large number of ETL/ELT features to support data integrations.
Informatica's PowerCenter and Informatica Cloud Data Integration synchronize data across various systems in real-time or scheduled batches. They support a broad range of data sources, including databases, cloud services, and on-premises systems. Users can map, transform, and cleanse data to ensure consistency and accuracy.
B2B/EDI Integration
MuleSoft supports B2B integrations through EDI message parsing and generation capabilities. It includes support for the AS2 protocol, commonly used in B2B communications. In addition, AnyPoint includes Partner Manager features to handle external data integrations and different data standards of partners.
Informatica's B2B Data Exchange facilitates the exchange of electronic documents with trading partners using standards like X12 and EDIFACT. It provides pre-configured EDI templates for documents such as orders, invoices, and shipping notices.
Application Integration
MuleSoft supports application integration through Anypoint Connectors for popular SaaS and on-premises applications. For custom applications, it offers a connector SDK. AnyPoint’s Flow Designer provides a visual environment for creating integration flows between different applications.
Informatica’s Cloud Application Integration connects various applications to streamline business processes across SaaS applications like Salesforce, NetSuite, and Workday. It includes low-code integration and workflow automation functionality.
System integration
As MuleSoft is owned by Salesforce, you can guarantee that they have deep ERP and CRM system integration capabilities. MuleSoft supports various system integration patterns, including real-time, batch, and event-driven architectures.
Informatica PowerCenter and Informatica Intelligent Cloud Services connect a wide range of enterprise systems including ERP, CRM, and HR platforms. These tools offer data transformation, error handling, and monitoring features, facilitating seamless data exchange and process automation.
Factors to consider when comparing MuleSoft and Informatica
MuleSoft and Informatica are both established enterprise software companies, but they approach integrations in different ways. Here are some factors to consider:
- Scalability and Performance:
Both MuleSoft and Informatica have a track record of large deployments. MuleSoft uses a clustered architecture for enterprise-scale deployments, while Informatica’s cloud-native architecture ensures scalability and high performance.
- Monitoring:
MuleSoft provides Anypoint Monitoring with customizable dashboards for oversight, while Informatica offers comprehensive monitoring and analytics through its Intelligent Data Management Cloud.
- Security and Compliance:
Both MuleSoft and Informatica have extensive security functionality. MuleSoft offers Anypoint VPCs for isolated network environments, while Informatica emphasizes data privacy and compliance with its data governance tools.
- Community and Ecosystem:
MuleSoft's ecosystem is generally larger and more established, reflecting its longer presence in the enterprise market. Informatica’s community is also robust, with a larger focus on data management professionals.
What changed for MuleSoft and Informatica in 2026
The most important change to this comparison is that it is no longer a comparison between two companies.
Salesforce completed its acquisition of Informatica on 18 November 2025, in a deal valued at roughly $8bn, positioning Informatica's data management alongside MuleSoft and Salesforce's agentic-AI data foundation. Salesforce has owned MuleSoft since 2018. Both platforms in this comparison now sit inside the same organisation.
That does not make either product worse, and Informatica has continued to operate across clouds since the deal closed, expanding its Microsoft Fabric and Azure integration in March 2026. But it changes the questions worth asking:
- Where do the two roadmaps overlap, and which product does Salesforce intend to lead with in the areas where they do?
- If you are buying both, what does the combined commercial relationship look like?
- If you deliberately chose two vendors for resilience, does that still hold?
These are reasonable questions to put to a Salesforce account team directly. Vendors expect them after an acquisition of this size.
MuleSoft also launched Agent Fabric, generally available from October 2025: Agent Registry, Agent Broker, Agent Visualizer and Agent Governance, a control layer for registering, routing, observing and governing AI agents built on any platform.
Why choose MuleSoft?
MuleSoft may be a good option for you if you’re consolidating your enterprise tech stack around Salesforce. It can handle most cloud-based integration patterns and a broad range of pre-built connectors to and from Salesforce apps.
MuleSoft highlights:
- API creation and integration capabilities.
- Supports automation with a large template library and RPA access.
- Wide capabilities in composite service integration.
Why Choose Informatica?
Informatica can be an option for you if your primary focus is on master data management and digital transformation. It offers comprehensive data integration and management solutions, making it ideal for complex data environments.
Informatica Highlights:
- Extensive data integration and management tools.
- AI-driven data processing and automation features.
- Strong focus on data governance and compliance.
ONEiO as an Alternative to MuleSoft and Informatica
If you’re not sure if MuleSoft or Informatica is the best option for your integration needs, you may consider a third alternative, ONEiO.
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ONEiO gives you a streamlined, no-code integration service that stands out for several reasons:
Effortless integrations as a service
While MuleSoft and Informatica have some low- and no-code functionality, ONEiO is the first integration platform that offers end-to-end integrations as a service. This is especially valuable in case you don’t plan to hire a full team of system integrators to maintain your integration ecosystem.
Integration automation beyond pre-built connectors
ONEiO supports a wide range of endpoint types and data formats, including JSON, XML, CSV, and plain text. It provides robust mechanisms for both push (using webhooks and REST/SOAP) and pull (via API, SFTP, SQL) data processing. This flexibility ensures that ONEiO can handle various integration scenarios with ease.
Security and compliance
ONEiO offers strong security features, including encrypted credentials and support for multiple authentication standards (Basic Authentication, Token, API Key, OAuth, etc.). It also allows connections to internal networks and supports reverse proxies or whitelisting. The platform is built on AWS and ensures high availability and GDPR compliance.
Business logic and data orchestration
ONEiO provides a no-code editor for creating business logic, transforming, and translating data. It supports various transformation options like regular expressions, case transformations, and date formatting. The platform’s rule robot automates rule creation based on common use cases, making it easy to adjust or add new rules without disrupting existing integrations.
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When to choose ONEiO?
ONEiO is especially well suited for seamless ITSM integration across internal and externally managed IT services. It offers a turnkey solution for the complex integration needs of both global enterprises and IT service providers.
ONEiO highlights:
- ONEAi artificial intelligence model trained specifically for IT service integration.
- Faster time-to-value. Typical integrations take 2 weeks from idea to production.
- 100% satisfaction guarantee based on proven enterprise-grade integration service.
What changes when integration is a service rather than a platform
ONEiO is a managed integration service, sometimes described as managed iPaaS. It delivers the same outcomes an iPaaS delivers, which is any-to-any connectivity, lifecycle management and cloud-native delivery, with one structural difference: ONEiO designs, runs, monitors and maintains the integrations, with SLA-backed outcomes and 24/7 operations. Customers decide how much control they keep.
Choose ONEiO when: you want integration outcomes without staffing an integration team. Choose VENDOR A or VENDOR B when you have mature in-house integration engineering and want maximum platform control.
One integration connects multiple endpoints. No point-to-point custom work for each new connection. Customer systems stay as they are and keep evolving independently. Adding the tenth partner costs roughly what adding the second one did.
"I don't care what kind of system the customer is using, we can connect any with any. And that is really one of the biggest benefits I see on ONEiO, which no other solution provider I know can promise or deliver." — Michael, MHP
Continuity is somebody's job. Microservices spread across geographic sectors with load balancing. Persistent queuing so data is not lost when a system on either end goes down. AI-powered monitoring 24/7/365. Upgrades, migrations and partner-side changes handled without breaking flows.
"Unbothered. I think that's the thing, how it changed us. We use our time to do other things, to monitor other things instead of the data exchanges." — Dmitri, Espoo
Outcomes are committed, not attempted. Integration specialists own security and compliance for the integrations themselves, not just for the platform underneath them. Issues are caught and resolved before they reach the business.
"ONEiO delivered that in three weeks, which is a remarkably great job." — Hanna, DNV
Who does the work?
Bottom line on MuleSoft vs Informatica
MuleSoft and Informatica were never really substitutes. MuleSoft connects applications through APIs. Informatica moves, cleans and governs data. Most large enterprises that use both use them for different jobs.
What changed is ownership. Since November 2025 both belong to Salesforce, which makes this less a vendor comparison than a portfolio question. Ask Salesforce where the overlap sits and what the plan is for each line.
If what you actually need is neither a data platform nor an API programme, but the integration layer between business systems kept running, that is a third category. ONEiO operates it as a service rather than selling you a platform to operate.
